8 August 2013 Racing out front, he was chasing the world record of 1:49.11 and managed to better it with a mark of 1:49.04. Russia’s Nikolay Skvortsov was a distant second, almost two seconds behind the South African star. SAinfo reporter He came close to defeating the favourite, Yannick Agnel, eventually finishing just 0.16 behind the Frenchman. His time was an African record of 3:37.91, which bettered the previous mark, set by Ryk Neethling in 2004, by a clear two seconds. He followed that up with a silver medal in the 50 metres butterfly, finishing just behind the winner, Germany’s Steffen Deibler, in a time of 22.22 seconds. Le Clos placed third, clocking 22.62. Outstanding performanceMyles Brown, who usually swims the 800 and 1 500 metres freestyle, moved up to the 400 metres and produced an outstanding performance. Roland Schoeman proved yet again that one should be judged on performance and not age. The 33-year-old sprint specialist raced to victory in the 50 metres breaststroke in a fast 25.85 seconds. The next Fina World Cup event takes place in Berlin, Germany, on 10 and 11 August. It has been a wonderful month for the 21-year-old Le Clos. At the Fina World Championships in Barcelona, he claimed two gold medals, doing the double in the 100 and 200 metres butterfly. His achievements, along with those of Cameron van der Burgh (gold in the 50m breaststroke and silver in the 100m) and Giulio Zorzi (bronze in the 50m breaststroke), helped South Africa finish a high ninth on the medal table. South African Olympic gold medallist Chad le Clos was in world record-setting form on Wednesday evening at the Fina World Cup in Eindhoven, The Netherlands, as South African swimmers shone in short course action. Competing in the 200 metres butterfly, Le Clos – who rose to fame by defeating the legendary Michael Phelps in the long course event at the London Olympics in 2012 – was in a league of his own.
American scientists are scheduling a major trial of an experimental HIV vaccine in South Africa in 2016, “the most feasible vaccine ever developed”. It will be one of largest single clinical testing processes done in South Africa.A new, extensive HIV vaccine trial will be started in South Africa in November 2016. (Image: Wikipedia)Brand South Africa reporterA successful early-stage HIV vaccine clinical trial in South Africa has prompted the expansion of the experimental vaccine regimen into a large clinical trial.The new study, called HVTN 702, is designed to determine whether the regimen is safe, tolerable and effective at preventing HIV infection among South African adults. It will use a new variation of the RV144 shot, an experimental HIV vaccine developed by the US’s National Institute of Allergy and Infectious Diseases (Niaid). The drug will be trialled in South Africa at the end of 2016.Tony Fauci @NIAIDNews: “Everyone was dying & we didn’t know why’ #HVAD https://t.co/HanbTbvfm9 pic.twitter.com/ZXad2e30B3— IAVI (@IAVI) May 18, 2016The HVTN 702 study will be led by Protocol Chair Dr Glenda Gray. Gray is the president and CEO of the South African Medical Research Council, research professor of paediatrics at the University of the Witwatersrand, Johannesburg, and a director of the Perinatal HIV Research Unit at Chris Hani Baragwanath Hospital in Soweto, South Africa.According to a post on the Niaid website by its director, Dr Anthony Fauci, RV144 promises to be able to cut HIV viral infections by a third, even more when the vaccine is tested in a real-world environment. Fauci is one of the global leaders in searching for a viable and affordable solution to the HIV/Aids pandemic.He says the new RV144 variation has been the most feasible vaccine ever developed. The trial will be one of largest single clinical testing processes done in South Africa.Niaid, co-funder of the trial, falls under the US National Institutes of Health, an agency of the United States Department of Health. It is responsible for global biomedical and health-related research, particularly in communicable diseases and life-threatening allergies.“A safe and effective HIV vaccine could help bring about a durable end to the HIV/Aids pandemic,” Fauci writes in the post, adding that “(it) is particularly needed in southern Africa, where HIV is more pervasive than anywhere else in the world.”In 2009, an early variation of the vaccine, developed by the US military, was trialled in Thailand. It consisted of a two-vaccine combination that cut the risk of HIV infection by 31% over three-and-a-half years.A small safety trial in South Africa of the latest variation found the new modified shots promising enough to warrant an expanded study in November 2016, pending regulatory approval.The South African trial will use 5 400 adult volunteers, each receiving five injections over a year, either vaccine or placebo shots. Results of the trial will be analysed and are expected to be released towards late 2020.“While we are making encouraging (overall) progress (in the fight against the disease) – new HIV infections have fallen by 35% globally since 2000 – the development of a safe and effective HIV vaccine would be the ultimate game- changer,” Fauci writes. The new design and schedule of the vaccine regimen scheduled for the South African trial have been adjusted to try to increase the magnitude and duration of vaccine-elicited immune responses.“Vaccine research (will) also continue in the laboratory, where scientists are investigating the use of potent antibodies that block a high percentage of global HIV strains from infecting human cells.”In May 2016, South African Health Minister Aaron Motsoaledi announced that antiretroviral medicine would be made available to all HIV-positive people irrespective of their CD4 count by September. An extra R1-billion has been allocated to the health budget to make this programme possible.Watch a full presentation by Fauci on the new trial and HIV/Aids research work done by the National Institute of Allergy and Infectious Diseases.Source: News24Would you like to use this article in your publication or on your website? See Using Brand South Africa material.