Beanstalk Festival Drops 2018 Lineup With Biscuits & Motet Members Jam, Aqueous, Ghost Light, & More

first_imgToday, Colorado jam outfit The Magic Beans have announced the initial lineup for the 2018 edition of their Beanstalk Music & Mountains Festival. The host band will perform all three nights of the Rancho Del Rio festival, which will take place from June 28th through 30th in Eagle County, Colorado.Beanstalk Festival joins together the awe-inspiring beauty of the Rocky Mountains and Colorado River with a live music experience of some of the top touring and local acts and musicians. In addition to The Magic Beans’ host sets, this year’s initial lineup includes headlining performances from Horseshoes & Hand Grenades and Aqueous, in addition to the Beanstalk All-Star Superjam featuring Marc Brownstein and Aron Magner of The Disco Biscuits, Dave Watts of The Motet, Matt Jalbert of TAUK, and more.The down-bill for Beanstalk Music & Mountains Festival 2018 is equally impressive, with performances by Octave Cat, a side project featuring Jesse Miller of Lotus, Eli Winderman of Dopapod, and Charlie Patierno; Ghost Light, the highly anticipated new band featuring Holly Bowling, Tom Hamilton, Steve Lyons, Raina Mullen, and Scotty Zwang; Cory Wong of Vulfpeck; and Colorado’s own Eminence Ensemble. The initial lineup rounds out with sets by Mungion, Cycles (x2), Lespecial (an original set and a “Lespecial Does Primus” set), Anoramora, Yak Attack, The Jauntee, and more.After multiple successful years, the intimate festival has become renowned in Colorado as one of the can’t-miss events of the summer. In addition to a consistently stellar lineup and slow-flow, Yin, and Kali Durga yoga offerings, Beanstalk’s prime location along the banks of the Colorado River allows attendees to enjoy the outdoors—including hiking, hot springs, cliff jumping, ATVing, and world-class mountain biking—before the music starts in the mid-afternoon.Tickets are available here. For more information about Beanstalk Music & Mountains Festival 2018, visit the event website or follow the event on Facebook.last_img read more

Baseball Instant Replay

first_imgIf you are the Cincinnati Reds, you probably wish that MLB would go back to letting umpires make the final decision on all plays on the field without doing instant replay.  It seems that every time they ask for a replay they lose, even though all their TV replays seem to show that they were right in their reason for asking for the replay.  If you don’t know, a group of umpires in New York go over the plays based on camera shots that are sent to them from the ball park.  There are no questions allowed on their decision.  If you do question, you are ejected immediately from the game.This in itself might be fine if they had enough cameras in all baseball parks to show the angles of a play that are present in pro football and basketball; however, in baseball it is the local feeds that have the replay so you do not have the myriad of cameras that have been placed in the football and basketball arenas.  It seems to me that if they want to continue with these replays, the MLB must require some type of camera on all four bases.  Until they do, the umpire’s eyes may still provide the best view.  After all, baseball did survive for well over a hundred years with all of us having to live with the umpire’s call.last_img read more

Sourav Ganguly and daughter Sana exchange playful banter on his IG post

first_imgAdvertisement b5kuNBA Finals | Brooklyn Vs9872Wingsuit rodeo📽Sindre E803xtw( IG: @_aubreyfisher @imraino ) o8jWould you ever consider trying this?😱ahnl4Can your students do this? 🌚Roller skating! Powered by Firework The President of BCCI, Sourav Ganguly and daughter Sana were seen exchanging a playful banter in an Instagram post. After the completion of the pink ball test match at Eden Gardens, Sourav Ganguly posted one picture of him at the closing ceremony of the match.Advertisement In that image, Sourav Ganguly was looking very much serious. So, in the comment of the post, his daughter Sana Ganguly commented,Advertisement “What is it that you’re not liking”.Sourav Ganguly also took the comment of his daughter lightly and told,Advertisement “That ur becoming so disobedient”.In the reply, Sana wrote,“Learning from you,”It was a playful banter between the father and daughter. In one previous interview, Sourav Ganguly was asked why most of his recent Instagram posts were with Sana. In the reply, Sourav Ganguly has answered that the pressure at work is increasing for him day by day and he is missing his daughter badly at that moment.Sourav is currently the President of BCCI. He has successfully organized a pink ball day night test match in India for the first time. He has various plans in his mind to be implemented soon and certainly his vision will take Indian cricket to a next level.Watch: Adorable Ziva gives MS Dhoni a back massage and hugs him! Advertisementlast_img read more

Kortney Rose Foundation Hits $1M Mark

first_imgWork inspired by 9-year-old Oceanport girlBy Carol Gorga Williams / Photos by Jaclyn ShugardOCEANPORT – As 540 walkers and runner took their mark at a fun run at Kortney’s Challenge Sunday at Monmouth Park, the charity that bears her name, the Kortney Rose Foundation, celebrated 10 years of fundraising for what some supporters believe is the oft-neglected cause of research into pediatric brain tumors.The charity was begun just five months after Kortney Rose Gillette of Oceanport died from an inoperable brain tumor by her mother, Kristen. She and her husband Rich and their daughter Kasey, and those may have been reasons enough but she wanted to accomplish more.“At the time I started, I had no idea where it was going to go,” said Gillette whose foundation grew out of the Kortney Rose Care Foundation, a group of neighbors who helped the family as Kortney battled the tumor. But as Kristen Gillette’s knowledge of pediatric brain tumors grew, so did her determination to do something to help the research “especially after I heard the facts that so little is donated to brain cancer, especially brain tumors.”Little by little, the foundation’s impact grew until this April it passed the $1 million mark, with all the money going to pediatric brain tumor research at the Children’s Hospital of Philadelphia (CHOP) where Kortney was treated.“I’m still a little shocked,” confessed Gillette of the million-dollar-mark.Sunday’s event raised some $64,000, substantially higher than last year’s total of $42,000.“This year has been phenomenal in all aspects.”Robin Hurd, 50, of Long Branch invited her good friend Sandra Williams, 48 of Long Branch to do the 2-mile Challenge. Hurd is a brain tumor survivor of 16 years, and talking about her experience as she waited to join the race brought tears to her eyes. “I’ve been wanting to do the walk for years, but I always had some excuse. But finally yesterday, I just felt like I needed to come.”Elisabeth Maguire, 12, said she and her friend Elizabeth Norton, also 12, and both of Little Silver, wanted to be at Kortney’s Challenge because “You can get trophies. You feel so accomplished, and you feel like you did a good thing.”Opal Lachcik, 8, of Shrewsbury said the race gave her a warm feeling. “We’re doing it for someone, and it feels special,” she said.Participating in the Challenge is also a way for folks to honor someone who touched them. Hannah Duffy of Long Branch and Jeff Madonna of Red Bank ran to remember a Monmouth Regional student who died too soon. “It’s a great way to remember someone, and also bring attention to the need to raise money for brain tumor research,” said Madonna.The money goes directly to CHOP, into two projects including the Children’s Brain Tumor Tissue Consortium in Neurosurgery, according to the foundation.“She is just such an amazing inspiration and a powerhouse in her dedication,” said Jena V. Lilly, consortium project manager, said of Gillette. “It is her vision and being a true partner for the advancement of science. She is great friend and I am so grateful she is part of the program.”The feeling is so mutual. So mutual in fact that Gillette is devoted to the cause.“Sometimes because I work full-time and I do this, I don’t have a lot of time to myself,” she admitted although daughter Kasey is away at Montclair State, studying costume design so her mom’s guilt about home time is less.“When it started, I needed to direct my upset into something positive,” she said. “It kind of saved my life having the foundation in the beginning. Now I cannot imagine not doing it.”Others say Gillette’s work has made a difference beyond the dollars she has collected. Just last year, she was named a New Jersey Monthly “Seed of Hope” for her work in the community. She was instrumental as well in convincing the state Legislature to set aside May as Brain Tumor Awareness Month” in the state.“She has been doing the work of bringing other people to the same space she is in,” said Adam Resnick, director of the consortium. “She and her foundation have been fantastic supporters. As a result of her support over the longterm, she has been a conduit….for (attracting) a network of like-minded people who provide a support system for each other but form a larger network…Her contribution far extends beyond the million dollars.”It starts, he said, when patients’ families find the foundation on the web and begin the process of educating themselves about CHOP research efforts.“Her authentic contribution far exceeds the million dollar number,” said Resnick who also serves as director of Neurosurgical Translational Research. “The million dollars is amazing but her value to our organization and what we are doing helps form collaborative efforts. That vision is what she is advocating for educating other families about what we are about.”Getting the message out can help convince people of the importance of the issue and the work of the consortium, which is one of the country’s largest repositories for brain tumor tissue samples where any scientist with a research proposal is welcome as the experts work to unlock the mysteries of cancer.“We are finally gaining momentum, they are coming to us,” Gillette said of sponsors and others. The foundation has a number of corporate sponsors and she is grateful for support, large and small. The foundation reached $1 million over time and with the help of nickels from school children, a program called Kortney’s Coins.“I think initially it started as an Oceanport thing,” Gillette said of the small Monmouth County community the family calls home. “My intention was to expand out of Oceanport” and sponsors like Monmouth Park and the Turning Point help do that because they have a wider reach.Turning Point Restaurants earlier this year raised more than $51,000 for the foundation. But more than that, said Gillette, it enhanced the foundation’s visibility,” Gillette said. “That is my No. 1 thing. There are plenty of other people saying that. It is not just me being that good,” she said.last_img read more

Unsustainable loans will harm future generations – Jagdeo warns

first_img…expresses concern over $30B bond, possible collusion with NICIL Expressing concern over the Government’s borrowing habits and the recent revelations that over $100 million was paid to arrange a government-backed bond, Opposition Leader Bharrat Jagdeo is warning of the future consequences of these decisions.At his most recent press conference, Jagdeo noted that unsustainable levels of borrowing can have detrimental effects for Guyana as a whole. He referenced other economic variables, like the Bank of Guyana’s Statement of Assets and Liabilities showing billions of dollars in overdraft.President David Granger“We’ve pointed out that unsustainable levels of borrowing will harm our country in the future… (billions of dollars) overdraft at the central bank, US$150 million of development borrowing,” Jagdeo said.“The Minister of Finance (Winston Jordan) was in the Middle East talking about closer relationships with the Islamic Bank and he has already signalled that he intends to borrow some US$900 million there.”Jagdeo also zeroed in on the $30 billion bond that was negotiated by the Special Purpose Unit (SPU) for the Guyana Sugar Corporation (GuySuCo). According to Jagdeo, he warned President David Granger about the pitfalls of this transaction.“I sat with the President. I said to him, ‘this is not necessary, because you’re not using the money now’. He did absolutely nothing about it. Now there is a raging controversy between the Agriculture Ministry and the SPU and he does not intervene.”According to Jagdeo, the former People’s Progressive Party/Civic (PPP/C) Administration never arranged a bond of this magnitude, much less paid such a large arranger fee. In addition, the former President expressed concern over possible links between the point person for the bond and a member of the National Industrial and Commercial Investments Limited (NICIL) Board.“That, if it is true, is really a serious issue. That would explain the rush to raise all of the money –because the arranger then gets a percentage – even though you do not need the money now and even though the taxpayers have to pay a 4.75 per cent interest,” Jagdeo observed.Earlier this year, NICIL acquired the $30 billion syndicated bond at a rate of 4.75 per cent interest to spend on capitalising GuySuCo’s remaining estates. It subsequently emerged that part of the bond was used by GuySuCo to repay interest on another debt.As the bond has strict requirements for how it would be used, Republic Bank Managing Director Richard Sammy wrote to the bond trustees – Hand-in-Hand Corporation, to complain. The Bank also called for a full explanation as to the apparent breach of the terms of the Trust Deed.Hand-in-Hand had written to Republic Bank requesting that the purpose of the Trust Deed be changed regarding how the proceeds of the bond shall be applied. While Republic Bank has stated its no objection to the proposed changes to the Trust Deed, it said it remained disappointed that proceeds from the bond were utilised for a purpose other than what was approved.The SPU has not taken lightly criticisms which seek to suggest that the bond would be wasted and that it was acquired at an unreasonable rate. In fact, the SPU had said it should be noted that, as standard for any debt financing, security is required to secure payments to bondholders.The term of the bond is five years, since it is expected that the proceeds of the land sale for GuySuCo would be used for repayment. But Agriculture Minister Noel Holder himself has been publicly critical of the transaction.last_img read more

Consumer confidence levels at 18-month low

first_imgThe overriding worry, though, is that consumers will cut back on their spending, dealing a blow to the economy. “There are definite risks if people get sufficiently spooked,” said Bill Cheney, chief economist at John Hancock Financial Services Group. “If you believe the only thing we have to fear is fear itself, well, we got the fear, so we better fear it,” he said. A measure looking at peoples’ attitudes about investing, including their comfort in making major purchases, fell to 88.3 in September, from 97.9 in August. Individuals’ feelings about the economy’s prospects and their own financial fortunes over the next six months plunged to 14.4, compared with 43.9 in August. The new reading was the fourth weakest showing on record. Peoples’ feelings about current economic conditions, meanwhile, slid to 90.5 in September, from 105.6 in August. Credit problems in mortgage and other markets make it likely the worst housing slump in 16 years will persist well into 2008. Foreclosures and late payments are spiking. Lenders have been forced out of business. The carnage has wreaked havoc on Wall Street. Economic growth in the current July-to-September quarter is expected to slow to an annual rate of around 2 percent. That would be half the pace logged in the April-to-June period and would constitute a subpar performance. With growth cooling, the job market – and wage growth – also could lose ground. The first major crack appeared in what had been a mostly sturdy employment environment when the government reported last week that employers cut 4,000 jobs in August. It was the first monthly decline in national payrolls in four years. A measure tracking consumers’ sentiments about employment conditions dropped to 113.6 in September, the weakest reading in nearly 1 years.160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! Against this backdrop, analysts say the chance the economy might fall into a recession is growing. Still many are counting on the Federal Reserve to cut interest rates next week. Such a move could give people and companies an important psychological boost. It also might make them more inclined to spend and invest, which could help energize economic activity. Economists keep close tabs on confidence barometers for any clues about consumers’ willingness to spend. Consumer spending accounts for a big slice of overall economic activity. In August, consumers spent moderately; it was also a month when their confidence had gone up. A government report Friday showed retail sales rose 0.3 percent last month, down from 0.5 percent in July. August’s gain, however, was smaller than analysts had expected. WASHINGTON – Shaken by housing and credit woes, peoples’ confidence in the economy sank to its lowest point in nearly 1 years, raising fresh worries about their appetite to spend in the months ahead. The RBC Cash Index showed consumer confidence clocking in at 71.1 in September, a sharp drop from August’s reading of 89.3. It marked the worst showing since May 2006. The index is based on the results of international polling firm Ipsos. “Consumers are rattled to the bone,” Richard Yamarone, economist at Argus Research, said of the latest confidence reading. The deterioration comes as Wall Street has been suffering through a mood swing of its own, sending stock prices careering wildly. The deeper consumer angst also comes after troubling news last week that the economy lost jobs for the first time in four years. last_img read more

Admissions of Ignorance in Evolutionary Theory

first_imgFor a scientific idea some have proclaimed as a fact no longer in need of proof, and as well-established as gravity, Darwin’s theory of evolution still reveals surprising weaknesses when its defenders speak about the details.  Detecting these weaknesses requires tuning out the media hype, and tuning into scientific papers and pro-evolution journals where evolutionary theory is debated.  Elisabeth Pennisi wrote one such account in Science last week.1  It revealed that the public is getting a very misleading view of evolution – both its operation and the strength of the evidence for it.    It would seem obvious that evolution needs a genetic basis.  Darwin attempted to explain it in his day, unsuccessfully.  The neo-Darwinian synthesis of the 1930s was supposed to explain it.  Serious questions about how evolution works at the genetic level remain, however, to this day.  This was evident in Pennisi’s use of war metaphors to describe two groups of evolutionists that are “locking horns” over a current issue: whether genes or regulatory elements (in particular, cis regulatory factors) are key to evolutionary change.  The latter, a “fashionable idea,” has been growing in popularity among those in the evo-devo subculture: i.e., evolutionary biologists who focus more on developmental than genetic influences.  When Jerry Coyne and Hopi Hoekstra wrote a pointed critique of the regulatory-element hypothesis in the journal Evolution last year, “Egos were bruised.  Tempers flared.  Journal clubs, coffee breaks at meetings, and blogs are still all abuzz,” she wrote.    None of the combatants doubt Darwin’s theory in the slightest, of course.  Still, some statements in Pennisi’s account could give a Darwin-doubter cause for gloating.  Consider this paragraph:[Sean] Carroll [U of Wisconsin] argued that mutations in cis regions were a way to soft-pedal evolutionary change.  Genes involved in establishing body plans and patterns have such a broad reach–affecting a variety of tissues at multiple stages of development–that mutations in their coding regions can be catastrophic.  In contrast, changes in cis elements, several of which typically work in concert to control a particular gene’s activity, are likely to have a much more limited effect.  Each element serves as a docking site for a particular transcription factor, some of which stimulate gene expression and others inhibit it.  This modularity makes possible an infinite number of cis-element combinations that finely tune gene activity in time, space, and degree, and any one sequence change is unlikely to be broadly disruptive.This sounds like damage control.  Is the standard explanation too risky?  Yet critics of the evo-devo alternative argue that every such “fine-tuning” change must be adaptive to persist through natural selection.  Precious few examples, they say, can be found to illustrate a regulatory change related to a morphological change.  One regulatory change in a mouse, for instance, can make its digits grow slightly longer (see 01/18/2008), but the mutant mouse is hardly ready to take off flying like a bat.    “Where’s the beef?” challenged Pennisi, giving the floor to Coyne and Hoekstra, who countered that mutations for evolutionary change must occur in genes:But Hoekstra and Coyne say this enthusiasm doesn’t rest on solid evidence.  In their Evolution article, they picked apart these examples and the rationale behind them.  They pulled quotes from Carroll’s work to criticize his fervor and berated the evo-devo community for charging full speed ahead with the cis-regulatory hypothesis.  “Evo devo’s enthusiasm for cis-regulatory changes is unfounded and premature,” they wrote.  Changes in gene regulation are important, says Hoekstra, but they are not necessarily caused by mutations in cis elements.  “They do not have one case where it’s really nailed down,” she says.Those be fightin’ words, indeed.  Coyne even used psychological warfare, telling Science, “I’m distressed that Sean Carroll is preaching to the general public that we know how evolution works based on such thin evidence.”    The opposition did not take this sitting down.  “Almost as soon as their article appeared, lines were drawn and rebuttals planned,” Pennisi reported like a war correspondent.  But did they come back with a knock-down case for evolution?  All Sean Carroll could reply was that his view is the best of a bad lot:“I am not trying to say that regulatory sequence is the most important thing in evolution,” he told Science.  But when it comes to what’s known about the genetic underpinnings of morphological evolution, “it’s a shutout” in favor of cis elements, he asserts.That one statement could come as a shock to students who have been taught all their lives that evolution by natural selection acting on genetic mutations is well understood.  The article degenerated from here into the battle of the T-shirts and other fluff.  Coyne, for instance, sported a T-shirt that said “I’m no CISsy,” and entitled his talk at a recent conference, “Give me just one cis-regulatory mutation and I’ll shut up.”    Pennisi reported statistics from pro-evo-devo people purporting to show the extent of regulatory elements involved in mutated genes.  “Yet even these data are inconclusive,” another was quoted admitting.  At the end of the article, there was no winner.  Pennisi’s closing theme, with variations, was how little is known.  Everyone was making excuses.  Evo-devo devotees complained that associations between regulatory elements and morphological effects are hard to measure.  “I really want to emphasize,” Carroll bluffed, “that evo-devo [researchers] haven’t come to this way of thinking simply through storytelling” but through data.  Was this a response to ridicule he has heard?  Or was it a backhanded charge that his opponents are the storytellers?  Either way, it’s hard to feel his conclusions are compelling when the relevance of certain regulatory elements, and their interactions, are confusing, and “the numbers may be misleading.”  How much more so when genetic mutations can affect the regulatory elements themselves?  What role do RNA elements play?  What about gene duplications?  Patricia Wittkop (U of Michigan) suggested there may be more noise than signal when she said, “The important question is about finding out whether there are principles that will allow us to predict the most likely paths of change for a specific trait or situation.”  It would seem any scientific claim needs such principles to be deemed scientific.    If the evolutionists cannot resolve their conflict, they can at least improve their battlefield protocols.  Pennisi ended with this:With so much unknown, “we don’t want to spend our time bickering,” says [Gregory] Wray [Duke U].  He and others worry that Hoekstra, Coyne, and Carroll have taken too hard a line and backed themselves into opposite corners.  Coyne doesn’t seem to mind the fuss, but Hoekstra is more circumspect about their Evolution paper.  “I stand by the science absolutely,” she says.  “But if I did it over again, I would probably tone down the language.”1.  Elisabeth Pennisi, “Evolutionary Biology: Deciphering the Genetics of Evolution,” Science, 8 August 2008: Vol. 321. no. 5890, pp. 760-763, DOI: 10.1126/science.321.5890.760.The vast majority of the public, including high school students, never sees the bickering between Darwiniacs over the most fundamental aspects of their theory.  That’s why you need to see it exposed here.    The lesson in this story is that almost nothing is understood in their tale at a scientific level.  Evolutionists want us to believe that humans have bacteria ancestors.  All the amazing structures in all of life had to emerge from a simple, primordial cell by some undirected biological process at the genetic level.  When it comes to positive evidence for such a fantastic, astonishing claim, the paltry best these true believers could exhibit were inconclusive effects of mutations or regulatory elements on existing complex species: reversible changes to the amount of armor on stickleback fish, bristles or the lack of them on fruit flies (with no idea whether they provide any adaptive advantage), slightly longer digits on mice, and other trivia.  When it comes to negative evidence, look at how both sides falsified each other.  The charges and counter-charges were hilarious.  They go like this:“You have no evidence.”“Oh yeah?  Well, we have a lot more than you!”This is like the Dumb and Dumber T-shirts you see friends wearing at amusement parks.  We’ve taken off the Darwiniacs’ white lab coats and shown you their T-shirts: not just Dumb and Dumber, but Fussy and Fussier, and Deceived and Deceiver.  Should such people be “preaching to the general public” that “they know how evolution works, based on such thin evidence”?  Look under the T-shirt and you see just a skeleton with no scientific fitness.  “Where’s the beef?” indeed.  These Popeyes (05/31/2005) will find no salvation in spinach (01/24/2005).  Their ID nemesis, already fit to the hilt, has already eaten it all.  Skinny lightweights only win in the cartoons.(Visited 76 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

Extensive HIV vaccine study planned in South Africa

first_imgAmerican scientists are scheduling a major trial of an experimental HIV vaccine in South Africa in 2016, “the most feasible vaccine ever developed”. It will be one of largest single clinical testing processes done in South Africa.A new, extensive HIV vaccine trial will be started in South Africa in November 2016. (Image: Wikipedia)Brand South Africa reporterA successful early-stage HIV vaccine clinical trial in South Africa has prompted the expansion of the experimental vaccine regimen into a large clinical trial.The new study, called HVTN 702, is designed to determine whether the regimen is safe, tolerable and effective at preventing HIV infection among South African adults. It will use a new variation of the RV144 shot, an experimental HIV vaccine developed by the US’s National Institute of Allergy and Infectious Diseases (Niaid). The drug will be trialled in South Africa at the end of 2016.Tony Fauci @NIAIDNews: “Everyone was dying & we didn’t know why’ #HVAD https://t.co/HanbTbvfm9 pic.twitter.com/ZXad2e30B3— IAVI (@IAVI) May 18, 2016The HVTN 702 study will be led by Protocol Chair Dr Glenda Gray. Gray is the president and CEO of the South African Medical Research Council, research professor of paediatrics at the University of the Witwatersrand, Johannesburg, and a director of the Perinatal HIV Research Unit at Chris Hani Baragwanath Hospital in Soweto, South Africa.According to a post on the Niaid website by its director, Dr Anthony Fauci, RV144 promises to be able to cut HIV viral infections by a third, even more when the vaccine is tested in a real-world environment. Fauci is one of the global leaders in searching for a viable and affordable solution to the HIV/Aids pandemic.He says the new RV144 variation has been the most feasible vaccine ever developed. The trial will be one of largest single clinical testing processes done in South Africa.Niaid, co-funder of the trial, falls under the US National Institutes of Health, an agency of the United States Department of Health. It is responsible for global biomedical and health-related research, particularly in communicable diseases and life-threatening allergies.“A safe and effective HIV vaccine could help bring about a durable end to the HIV/Aids pandemic,” Fauci writes in the post, adding that “(it) is particularly needed in southern Africa, where HIV is more pervasive than anywhere else in the world.”In 2009, an early variation of the vaccine, developed by the US military, was trialled in Thailand. It consisted of a two-vaccine combination that cut the risk of HIV infection by 31% over three-and-a-half years.A small safety trial in South Africa of the latest variation found the new modified shots promising enough to warrant an expanded study in November 2016, pending regulatory approval.The South African trial will use 5 400 adult volunteers, each receiving five injections over a year, either vaccine or placebo shots. Results of the trial will be analysed and are expected to be released towards late 2020.“While we are making encouraging (overall) progress (in the fight against the disease) – new HIV infections have fallen by 35% globally since 2000 – the development of a safe and effective HIV vaccine would be the ultimate game- changer,” Fauci writes. The new design and schedule of the vaccine regimen scheduled for the South African trial have been adjusted to try to increase the magnitude and duration of vaccine-elicited immune responses.“Vaccine research (will) also continue in the laboratory, where scientists are investigating the use of potent antibodies that block a high percentage of global HIV strains from infecting human cells.”In May 2016, South African Health Minister Aaron Motsoaledi announced that antiretroviral medicine would be made available to all HIV-positive people irrespective of their CD4 count by September. An extra R1-billion has been allocated to the health budget to make this programme possible.Watch a full presentation by Fauci on the new trial and HIV/Aids research work done by the National Institute of Allergy and Infectious Diseases.Source: News24Would you like to use this article in your publication or on your website? See Using Brand South Africa material.last_img read more

Ohio Ag Weather and Forecast, June 19, 2019

first_imgShare Facebook Twitter Google + LinkedIn Pinterest We should get some bonus dry weather today, but our next round of moisture is moving in a little quicker. So, that means we have clouds increasing today, with scattered showers arriving late this afternoon and evening. The action continues overnight through midday tomorrow, bringing .25″-1.5″ rains to about 90% of Ohio. should turn out mostly rain free, but we will likely see a few showers develop in the northern third of the state tomorrow late afternoon/evening. But, in a bit of a silver lining, since the moisture is moving in a little faster today, it will be out faster tomorrow, so we may start to see clouds break up tomorrow afternoon and evening. We still look for a dry Friday period over the entire state, but expect more sunshine than we previously were looking for.No change for the rest of the forecast this morning. This weekend, scattered showers and thunderstorms will move through with at least 2, and perhaps 3 waves from Saturday through Sunday and early Monday. Combined weekend moisture will be from .5”-2” with coverage at 100% of the state. Some of the weekend thunderstorms, particularly overnight Saturday night into Sunday, can be strong to severe. Rain tapers off Monday midday, and we should be dry by Monday afternoon.We are keeping the forecast drier for next Tuesday, Wednesday and the first part of Thursday. Temps stay near normal, but the lack of precipitation should allow for good evaporation. Watch for some scattered showers to re-emerge later next Thursday afternoon.  A look at rainfall totals through Monday is at right.last_img read more